When multiple myeloma relapses

Make your treatment choice count in patients who relapse for the 1st time

Despite substantial progress, the majority of patients with multiple myeloma still fail to achieve optimal response regardless of treatment regimen.1 Multiple myeloma currently remains incurable and most patients will relapse despite achievement of CR.1,2

In addition, as the disease progresses, clinical benefit decreases with each subsequent line of therapy.3

There continues to be an urgent unmet need for novel therapeutic approaches that provide high-quality response and symptomatic relief, and maintain a good quality of life for patients with relapsed or refractory multiple myeloma.4

Of patients receiving therapy after 1st relapse, 4 out of 10 do not start a therapy after 2nd relapse.5 Therefore, the strongest treatment should be chosen at first relapse.5

Remission duration decreases with each line of therapy

Please read the SmPC for full comprehensive safety information


  1. Martinez-Lopez J, et al. Blood 2014;123:3073–3079.
  2. Gay F, et al. Blood 2011;117:3025–3031.
  3. Kumar SK, et al. Mayo Clin Proc 2004;79:867–874.
  4. Dimopoulos MA, et al. Eur J Haematol 2011;86:1–15.
  5. Raab MS, et al. Br J Haematol 2016 [Epub ahead of print].

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